I ran into a situation where SuccessMaker would allow the students to log in but when they wanted to use one of the installed apps, the program would prompt for the CD. The school is running the Enterprise Edition of the software, so all apps are running from the server and do not require CDs.
The culprit turned out to be a drive mapping issue. Make sure that the drive you use for SuccessMaker is MAPPED and not just pointing via UNC. Also, make sure that the drive is mapped in the appropriate login script, so you will not have to map it on each machine manually.